Mannose-binding lectin gene polymorphism in Greek systemic lupus erythematosus patients
نویسندگان
چکیده
منابع مشابه
Mannose binding lectin gene polymorphism and preclinical carotid atherosclerosis in patients with systemic lupus erythematosus.
Patients with systemic lupus erythematosus (SLE) have increased risk of atherosclerosis and CVD that cannot be explained by traditional risk factors. Previous studies indicated that mannose binding lectin (MBL) may modify the development of atherosclerosis. This study was designed to investigate association of MBL gene polymorphism with occurrence of preclinical atherosclerosis in SLE. The stud...
متن کاملCodon 72 Polymorphism of p53 Gene and Hematologic Manifestations in Patients with Systemic Lupus Erythematosus
Background: Systemic lupus erythematosus is a systemic autoimmune disorder with unclear etiology. The importance of some genes in the development of systemic lupus erythematosus has been implicated. The gene polymorphism in codon 72 has attracted a lot of attention and its role in the occurrence or progression of many cancers and autoimmune diseases especially systemic lupus erythematosus has ...
متن کاملMannose binding lectin (MBL) in autoimmunity and its role in systemic lupus erythematosus (SLE).
Mannose binding lectin (MBL) is an important element of the innate immune system. MBL binding leads to activation and cleavage of C3 and C4 suggesting the role of MBL pathway for opsonization and/ phagocytosis. The role of adaptive immune response in development of pathogenic autoantibodies in various autoimmune diseases is well understood. The link between innate and acquired immunity is helpf...
متن کاملNeurobrucellosis in systemic lupus erythematosus
Background: Brucellosis is a zoonotic infection which is endemic in many countries. It is a multisystem disease which may present with a broad spectrum of clinical manifestations and complications. Neurobrucellosis is an uncommon complication of brucellosis. Case presentation: A 25-year-old woman with a history of lupus for 5 months referred to the emergency ward of Shahid Beheshti Hosp...
متن کاملMannose binding lectin: a biomarker of systemic lupus erythematosus disease activity
INTRODUCTION A role for mannose binding lectin (MBL) in autoimmune diseases has been demonstrated earlier and elevated level of MBL has been shown in systemic lupus erythematosus (SLE) patients. In the current study, we investigated MBL as a potential biomarker for disease activity in SLE. METHODS In a case control study SLE patients (93 females) and 67 age, sex, ethnicity matched healthy con...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Rheumatology
سال: 1997
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/36.11.1238b